(a.) (Neither a material molecule, nor a material aggregation of material atoms could possess life and intelligence.) First, let us consider the nature of this alleged soul-body. As every soul necessarily possesses life, and as the body, considered as being the soul, must obtain at least two molecules, if not more (there are three possibilities): either only one of them possesses life, or all of them possess it, or none of them. If one molecule alone possesses life, it alone will be the soul. Of what nature will be that molecule supposed to possess life by itself? Will it be water (Hippo), air (Anaximenes, Archelaus, and Diogenes), earth, or fire (Heraclitus, Stobaeus?) But those are elements that are inanimate by themselves, and which, even when they are animated, possess but a borrowed life. Still there is no other kind of body. Even those (philosophers, like the Pythagoreans) who posited elements other (than water, air, earth and fire) still considered them to be bodies, and not souls, not even attributing souls to them. The theory that life results from the union of molecules of which, nevertheless, none by itself possesses life, is an absurd hypothesis. If further any molecule possesses life, then a single one would be sufficient. [Ennead IV,7 (2) 2]

The most irrational theory of all is that an aggregation of molecules should produce life, that elements without intelligence should beget intelligence. Others (like Alexander of Aphrodisia) insist that to produce life these elements must be mingled in a certain manner. That would, however, imply (as thought Gallen and Hippocrates) the existence of a principle which produces order, and which should be the cause of mixture or, temperament, and that should alone deserve being considered as soul. No simple bodies could exist, much less composite bodies, unless there was a soul in the universe; for it is (seminal) reason which, in, adding itself to matter, produces body. But surely a (seminal) reason could proceed from nowhere except a soul. [Ennead IV,7 (2) 2]

(b.) (No aggregation of atoms could form a whole that would be one and sympathetic with itself.) Others, on the contrary, insist that the soul is constituted by the union of atoms or indivisibles (as thought Leucippus, Democritus and Epicurus.) To refute this error, we have to examine the nature of sympathy (or community of affection, a Stoic characteristic of a living being,) and juxtaposition. On the one hand an aggregation of corporeal molecules which are incapable of being united, and which do not feel cannot form a single sympathetic whole such as is the soul, which is sympathetic with herself. On the other hand, how could a body or extension be constituted by (a juxtaposition of) atoms? [Ennead IV,7 (2) 3]

(i.) (Souls cannot, as do bodies, lose or gain parts, ever remaining identical.) The body has the faculty of making its organs grow within a definite time and in fixed proportions. From where could the soul derive them? Its function is to grow, not to cause growth, unless the principle of growth be comprehended within its material mass. If the soul that makes the body grow was herself a body, she should, on uniting with molecules of a nature similar to hers, develop a growth proportional to that of the organs. In this case, the molecules that will come to add themselves to the soul will be either animate or inanimate; if they are animate, how could they have become such, and from whom will they have received that characteristic? If they are not animate, how will they become such, and how will agreement between them and the first soul arise? How will they form but a single unity with her, and how will they agree with her? Will they not constitute a soul that will remain foreign to the former, who will not possess her requirements of knowledge? This aggregation of molecules that would thus be called soul will resemble the aggregation of molecules that form our body. She would lose parts, she would acquire new ones; she will not be identical. But if we had a soul that was not identical, memory and self-consciousness of our own faculties would be impossible. [Ennead IV,7 (2) 5]

Shall we have to admit that composition and decomposition are movements which exist by themselves, and analyze alteration into them? Condensation is explained as undergoing an alteration; that means, as becoming composite. On the other hand, rarefaction is also explained as undergoing an alteration, namely, that of decomposition; when, for instance, one mingles water and wine, each of these two things becomes other than it was, and it is the composition which has operated the alteration. We will answer that here composition and decomposition no doubt precede certain alterations, but these alterations are something different than compositions and decompositions. Other alterations (certainly) are not compositions and decompositions, for neither can condensation nor rarefaction be reduced to these movements, nor are they composed of them. Otherwise, it would be necessary to acknowledge the (existence of) emptiness. Besides, how could you explain blackness and whiteness, as being composed of composition and decomposition? This doctrine would destroy all colors and qualities, or at least, the greater part of them; for if all alteration, that means, all change of quality, consisted in a composition or decomposition, the result would not be the production of a quality, but an aggregation or disaggregation. How indeed could you explain the movements of teaching and studying by mere “composition”? [Ennead VI,3 (44) 25]

Since the work under consideration is the entire world, we would, were our intelligence attentively to listen to its voice, hear it exclaim as follows: “It is a divinity who has made Me, and from the divinity’s hands I issued complete, including all animated beings, entire and self-sufficient, standing in need of nothing, since everything is contained within Me; plants, animals, the whole of Nature, the multitude of the divinities, the troupe of guardians, excellent souls, and the men who are happy because of virtue. This refers not only to the earth, which is rich in plants and animals of all kinds; the power of the Soul extends also to the sea. Nor are the air and entire heaven inanimate. They are the seat of all the excellent Souls, which communicate life to the stars, and which preside over the circular revolution of the heaven, a revolution that is eternal and full of harmony, which imitates the movement of Intelligence by the eternal and regular movement of the stars around one and the same centre, because heaven has no need to seek anything outside of itself. All the beings I contain aspire to the Good; all achieve Him, each according to its potentiality. Indeed, from the Good depends the entire heaven, my whole Soul, the divinities that inhabit my various parts, all the animals, all the plants, and all my apparently inanimate beings. In this aggregation of beings some seem to participate only in existence, others in life, others in sensation, others in intelligence, while still others seem to participate in all the powers of life at one time; for we must not expect equal faculties for unequal things, as for instance sight for the fingers, as it is suitable to the eye; while the finger needs something else; it needs its own form, and has to fulfil its function.” [Ennead III,2 (47) 3]